Disabling cosmetic filtering by default will prevent the element picker and zapper from manifesting, when called from either toolbar icon or context menu.
Verified by creating new profile, changing the add-on signature requirement in about:config, installing uBO and toggling the cosmetic filtering setting. No further changes from default Firefox or uBO configuration.
https://github.com/gorhill/uBlock/releases
Duplicate of #2963.
My mistake, this is not a duplicate.
I can reproduce it in Chromium 66 too.
The element picker for me does not working at all. Just tested it on a fresh Firefox profile, installed uBlock and it's not working.
Most helpful comment
The element picker for me does not working at all. Just tested it on a fresh Firefox profile, installed uBlock and it's not working.