There is a big problem with the performance of the AutoColumnSize plugin. It seems that the calculation done by the plugin takes a very long time even for tables with a simple configuration. It's also noticeable for cooperation with TrimRows, HiddenRows and HiddenColumns plugins which was mentioned within https://github.com/handsontable/handsontable/pull/7223. The below image shows a bottleneck occurrence just after untrimming rows.

Please keep in mind that @aarondfrancis mentioned some kind of improvement within https://github.com/handsontable/handsontable/issues/6676 which should be also considered.
Happy to help if I can!
Most helpful comment
Happy to help if I can!