Upon trying to open the game, I would get this error and the game would refuse to launch.
Game won't launch, instead getting this error:

Launch game>crash.
Game would launch normally, any error afterwards being unrelated.
CRASH LOG BELOW
crash.log
Cataclysm DDA version 0.E-3388-gc2cd66c
Nothing to add, just suddenly happened.
Try renaming your config/ directory.
Nothing.
I even moved the config to a different folder, same issue.
How about save/?
Same crash, again I moved the folder to another folder.
Also unrelated, but nice PFP, reminds me of something from another mod for Starbound.
Something is off with tilesets. Your fresh install should work.
Something is off with tilesets. Your fresh install should work.
I figured as much, did a reinstall of everything before I checked back here, had an issue which I solved (if you have one mod in the root cdda mods folder and that same mod in data/mods it would cause a black screen, and infinite loading). Works now, thanks for the help folks.
I'll close this since this appears to be resolved then.
Most helpful comment
Something is off with tilesets. Your fresh install should work.