Seems to work fine on my Firefox 51 nightly with multiprocess enabled, just need to add "multiprocess": true to the package.json after more confirmation.

Works for me with Firefox Developer Edition 50 which is e10s enabled. So I agree that the manifest should be updated to report the addon as compatible so that it does not block the e10s rollout:
Firefox 50 was just released where e10s is enabled if all addons have the manifest property - would be nice to have this in :-)
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Firefox 50 was just released where e10s is enabled if all addons have the manifest property - would be nice to have this in :-)