With Karabiner-Elements active, the hold command|alt spacebar shortcuts for Siri in macOS Sierra are not working. This is not a big deal, but maybe still worth the bug report.

Thanks for the effort of getting Karabiner to work with macOS Sierra!
Thank you for feedback!
I've fixed this issue at v0.90.33.
Please upgrade to the latest version from "Misc > Check for updates" or
https://pqrs.org/latest/karabiner-elements-latest.dmg
Thanks for the fix! I found a remaining strange behaviour. After having installed the update (was v0.90.34 now), it did not work. I rebooted, after which it worked. However, once I changed the shortcut again (e.g. from hold command space to hold option space), it stopped working again (even if I change back to hold command space). Let me know if there is anything I can provide you that helps narrowing down this behaviour.
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Most helpful comment
Thank you for feedback!
I've fixed this issue at v0.90.33.
Please upgrade to the latest version from "Misc > Check for updates" or
https://pqrs.org/latest/karabiner-elements-latest.dmg