How can I login from the database Identityserver4 earlier in identityserver3 with the customer IUserService reached the breakpoint, but with the version v4 never reaches the GetProfileDataAsync method , the client always returns "Internal Server Error"

We'd need more details - check the logs.
I have not any .log error, because it is not an exception.
I need to authenticate with the database.
Adding users in memory works:

But I can not have static users, as they can change their data.
And it does not work:

I need my client's call enters the method GetProfileDataAsync:

You need to understand the sample host and how it related to IdSvr4 (it's different than in IdSvr3). Here's a sample that has taken the sample host and applied ASP.NET Identity 3 to it: https://github.com/tibold/IdentityServer4.Contrib.AspNetIdentity
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You need to understand the sample host and how it related to IdSvr4 (it's different than in IdSvr3). Here's a sample that has taken the sample host and applied ASP.NET Identity 3 to it: https://github.com/tibold/IdentityServer4.Contrib.AspNetIdentity