Thank you for opening the issue.
We will unbundle libressl in upcoming 2.3 series. We will continue to use libressl-2.4.6 for 2.2 series to preserve NPN support; it has been dropped in 2.6.3.
Concerning NPN, can I currently use H2O 2.2.3 with LibreSSL 2.6.3?
I think you can. You might need to set PKG_CONFIG_PATH to the <PREFIX>/lib/pkgconfig where PREFIX is your OpenSSL / liberssl installation directory, or use a more specific way (i.e. those descirbed in https://cmake.org/cmake/help/latest/module/FindOpenSSL.html#hints).
Most helpful comment
Thank you for opening the issue.
We will unbundle libressl in upcoming 2.3 series. We will continue to use libressl-2.4.6 for 2.2 series to preserve NPN support; it has been dropped in 2.6.3.