https://play.google.com/store/apps/details?id=com.soundcloud.android
Username: @debmaj2
Screenshot 1

Screenshot 2

Information | value
--- | ---
Platform: | Android 10
AdGuard product: | AdGuard for Android v3.4 (120)
AdGuard mode: | VPN
Filtering quality: | High-quality
HTTPS filtering: | enabled
DNS requests blocking: | enabled
Filters: | Ad Blocking:
AdGuard Mobile Ads,
AdGuard Base
Privacy:
AdGuard Tracking Protection
Social Widgets:
AdGuard Social Media
Annoyances:
AdGuard Annoyances
Custom filter subscriptions: |

@debmaj2 Hi. Could you please check with:
DNS requests blocking - disabled;Works fine on disabling DNS Filtering.
Ok. Not please check:
DNS Filtering + DNS Filter Enabled - Problem Happens.
DNS Filtering Enabled + DNS Filter Disabled - No Problem.
Great.
Please setup DNS filtering enabled, DNS filter enabled, DNS - any but not AdGuard, open and clear filtering log, and reproduce an issue after that. Then open filtering log and make screenshots of blocked requests or copy blocked domains.
Also you can try to unblock them one by one to find bad rule.
@debmaj2 Hi. Any news?
Screenshot:

Profile Screen with AdGuard "On"
Screenshot:

Profile Screen with AdGuard "Off"
@debmaj2
Got it. Could you please try to unblock blocked domains and check again?(tap=>unblock)
@Alex-302 the domain which is blocked is a malicious tracker often leading to unpermissive data hoarding like the Cambridge Analytica and rightly blocked. Just put the domain in a search and you will see numerous articles are raising concerns against the analytics company and their data collection practices.
So the app is not broken by blocked domains?
Please check AdGuard DNS without blocking
176.103.130.136
176.103.130.137
Reverting back to System DNS does not cause any issue. Issue is with Adguard DNS.
I mean not revert. Please check with this server
176.103.130.136
176.103.130.137
Should I add them as DNS in add Custom DNS option in Adguard App or in Phone Settings DNS field?
In AdGuard app.
Most helpful comment
DNS Filtering + DNS Filter Enabled - Problem Happens.
DNS Filtering Enabled + DNS Filter Disabled - No Problem.